Thursday, October 13, 2016

Treatment for Acute Intermittent Porphyria #1 - Glucose Admistration

Regarding to treatment for AIP, there was two types of main and specific treatment to control acute attack from AIP which was including the glucose administration and heme treatment.  Most of the findings recommended the patients administered the glucose intravenously or orally.  Intravenous glucose refer to the injection of the glucose directly into the bloodstream (Lundbaek, 1962).  According to Sezgin (2016), sixty percent of the patients had administered the glucose intravenously in order to control the acute attack of AIP and cure the AIP.  Another notable point for administered the glucose was glucose administration intravenously or orally could not function at all during the fasting period (Sezgin, 2016).

Figure 26Intravenous glucose 

According to Thomas (2015), patients usually administered intravenous glucose in water solutions in order to prevent excessive in hyponatremia.  On the contrary, one of the prior findings reported the contradictory findings compare with Thomas’s study. This past study emphasized that intravenous glucose in water solution was necessary to be aware and not to be used due to it can increase the risk of hyponatremia (Stein et al., 2012).

Figure 27. Types of hyponatremia

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