Thursday, October 13, 2016

Reducing Risks For Acute Intermittent Porphyria #4 - Hormones

For women, occurrence of acute attack is often associated with their menstrual cycle. Hormonal therapy can applied to manage this, that women took the contraceptive pills that control the hormone fluctuation and prevent suffer from AIP attack (Grob, Honcamp, Daume, Frank, Dusterberg, & Doss, 1995). Commonly this type of exogenous therapy will be used if the biopsychosocial model are not sufficient. However, there is the possibility that contraceptive pills will provoke 5% to 14% of acute attack of both latent and manifest AIP. Thus the clinician or physician should evaluated the benefits as well as risks prior this (Andersson, Innala, & Backstrom, 2003; Pischik & Kauppinen, 2015). In addition, parents who are the AIP carriers but would like to have children would go for genetic testing and genetic counselling (Balwani & Desnick). Through these, they are able to know the chances of having a child with AIP, this helps to lower the risks of passing the detective gene to the next generation. All in all, there is not possible to prevent suffer from AIP, but avoid of the precipitating factors and some of the genetic checking may contribute to a later presentation or even no presentation of an acute attack.

Figure 24. Contraceptive pills

No comments:

Post a Comment